Genetic Relationships of North Indian Populations
Author Information
Author(s): Khan Faisal, Pandey Atul Kumar, Tripathi Manorma, Talwar Sudha, Bisen Prakash S, Borkar Minal, Agrawal Suraksha
Primary Institution: Sanjay Gandhi Post Graduate Institute of Medical Sciences
Hypothesis
What are the genetic affinities between endogamous and inbreeding populations of Uttar Pradesh?
Conclusion
North Indians, especially upper caste and Muslim populations, are genetically closer to Caucasians than to East Asians.
Supporting Evidence
- North Indians showed a stronger genetic relationship with Europeans compared to Asians.
- Upper caste Brahmins and Muslims were closest to Caucasians.
- Middle caste populations were found to be closer to Asians.
Takeaway
This study looked at the genes of people in North India and found that they are more similar to Europeans than to Asians.
Methodology
The study genotyped 20 STR markers among 1800 samples from nine endogamous populations in Uttar Pradesh.
Potential Biases
Potential bias due to the endogamous nature of the populations studied.
Limitations
The study may not fully capture the genetic diversity of all Indian populations due to its focus on specific regions and groups.
Participant Demographics
Participants were adult individuals from nine endogamous populations in Uttar Pradesh, with a mean age of 38.8 years.
Statistical Information
P-Value
0.0341
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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