Heterogeneity in Health Outcomes in the Strong Hearts, Healthy Communities-2.0 Multilevel Intervention in a Community-Randomized Trial: An Exploratory Study of Moderators
2024

Exploring Health Outcomes in a Community-Based Intervention for Obesity

Sample size: 182 publication 10 minutes Evidence: moderate

Author Information

Author(s): Rethorst Chad D., Demment Margaret M., Ha Seungyeon, Folta Sara C., Graham Meredith L., Eldridge Galen D., Seguin-Fowler Rebecca A.

Primary Institution: Institute for Advancing Health Through Agriculture, Texas A&M University

Hypothesis

The study aims to identify factors associated with responses and non-responses to the Strong Hearts, Healthy Communities-2.0 intervention.

Conclusion

The SHHC-2.0 intervention was effective across a wide range of participants, with certain moderators like education level influencing outcomes.

Supporting Evidence

  • Participants with a high school education or less experienced less weight loss.
  • Those with a history of hypertension showed greater reductions in systolic blood pressure.
  • Participants with elevated depressive symptoms demonstrated greater weight loss.

Takeaway

This study looked at how different people responded to a program designed to help them lose weight and improve their health, finding that education and mental health played a big role.

Methodology

The study used a cluster-randomized controlled trial design over 24 weeks with women aged 40 and older in rural communities.

Potential Biases

Potential bias due to missing data and the predominantly White population of participants.

Limitations

The study was exploratory and not powered for moderation analysis, which may limit the reliability of the findings.

Participant Demographics

Participants were predominantly women aged 40 and older, living in rural communities, with a high percentage having a BMI over 30.

Statistical Information

P-Value

p<0.001

Confidence Interval

95%CI from -13.63 to -6.44 for weight loss based on education level.

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/nu16244353

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