Fine-needle aspiration of thyroid follicular lesions
Author Information
Author(s): Deveci M Salih, Deveci Güzin, LiVolsi Virginia A, Baloch Zubair W
Primary Institution: University of Pennsylvania Medical Center
Hypothesis
Is there a significant difference in the risk of malignancy between follicular neoplasm and follicular derived neoplasm in thyroid FNA specimens?
Conclusion
The study found that dividing thyroid follicular lesions into FON and FDN is important due to their significantly different malignancy rates.
Supporting Evidence
- The malignancy rate was 22% for FON and 72% for FDN.
- Almost half of the malignant cases in the FON category were papillary carcinoma.
- The risk of malignancy was higher in patients younger than 40 years.
- Malignancy rates were higher in males compared to females.
Takeaway
Doctors looked at samples from people's thyroids to see if they had cancer. They found that some types of thyroid lumps are more likely to be cancerous than others.
Methodology
The study involved evaluating 459 thyroid lesions diagnosed as FON and FDN with histopathologic follow-up.
Potential Biases
Potential bias in the selection of cases for analysis.
Limitations
The study is retrospective and may not account for all variables affecting diagnosis.
Participant Demographics
The participants ranged in age from 16 to 87 years, with 372 females and 87 males.
Digital Object Identifier (DOI)
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