Progress of Photodynamic Therapy in Gastric Cancer

Sample size: 80 publication Evidence: moderate

Author Information

Author(s): SEISHIRO MIMURA, HIROYUKI NARAHARA, TORU OTANI, SHIGERU OKUDA

Primary Institution: Osaka Medical Center for Cancer and Cardiovascular Diseases

Can photodynamic therapy (PDT) improve treatment outcomes for gastric cancer?

Improvements in techniques and instruments have led to a high cure rate for submucosal gastric cancer using PDT.

The overall cure rate for early gastric cancer was 56% with argon dye laser treatment.
The pulse laser improved cure rates to 84% overall.
Complete remission without recurrence was achieved in one case of advanced gastric cancer.

Doctors used a special light therapy to treat stomach cancer, and it worked really well for many patients.

Patients received photosensitizers followed by laser light irradiation, with careful management before and after the procedure.

The study did not include a control group for comparison and focused on patients who were poor risks for conventional surgery.

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