Duloxetine and Suicide Attempts: A Possible Relation
Author Information
Author(s): Salem Bilal A, Karam Elie G
Primary Institution: Saint George Hospital University Medical Center
Hypothesis
Is there a possible relation between Duloxetine use and increased risk of suicide attempts?
Conclusion
The study suggests that Duloxetine may be associated with the emergence of suicidality in some patients.
Supporting Evidence
- Both patients experienced increased irritability and depressive symptoms after starting or increasing Duloxetine.
- The emergence of suicidality occurred within a few days of medication changes.
Takeaway
This study looks at two women who tried to harm themselves after starting or increasing their Duloxetine medication, suggesting it might make some people feel worse.
Methodology
Case reports of two patients who attempted suicide while on Duloxetine.
Potential Biases
Potential bias due to the small sample size and reliance on case reports.
Limitations
The study is based on only two case reports, limiting generalizability.
Participant Demographics
Two married females, aged 30 and 47.
Digital Object Identifier (DOI)
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