Genetic Markers for Polled Trait in Holsteins
Author Information
Author(s): Cargill Edward J, Nissing Nick J, Grosz Michael D
Primary Institution: Monsanto Company
Hypothesis
Can we identify single nucleotide polymorphisms (SNPs) associated with the polled trait in Holsteins?
Conclusion
The study identified 13 novel SNPs associated with the horned/polled trait in Holsteins, which may serve as a genetic test panel for the breed.
Supporting Evidence
- The study identified 13 SNPs that are concordant with the horned/polled trait.
- Three of the identified SNPs are located in gene coding or regulatory regions.
- The 3'UTR SNP may disrupt a microRNA target site, potentially affecting gene expression.
Takeaway
Scientists found some tiny changes in the DNA of Holsteins that help tell if they will have horns or not, which can help farmers choose the right cows.
Methodology
The study sequenced approximately 160 kb of DNA from 12 polled and 12 horned Holsteins to identify SNPs in the polled region of bovine chromosome 1.
Limitations
The sample size was relatively small and the bulls were partially related, which may affect the generalizability of the findings.
Participant Demographics
The study involved 24 Holstein bulls, with 12 being polled and 12 being horned.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website