Nedocromil Sodium and Asthma in Children
Author Information
Author(s): A. Fiocchi, P. Signoroni, P. Bruni, M. Galeone, E. DeCet, S. Bogacki
Primary Institution: 5th Paediatric Department, University of Milan
Hypothesis
Does nedocromil sodium benefit urban asthmatic children with seasonal bronchial hyper-reactivity?
Conclusion
Nedocromil sodium can reverse bronchial hyper-reactivity caused by seasonal factors in children suffering from asthma.
Supporting Evidence
- Nedocromil sodium treatment showed a significant decrease in bronchial reactivity starting from day 7.
- Patients treated with nedocromil maintained good clinical conditions throughout the study.
- No significant differences were found in baseline spirometric parameters between the groups.
Takeaway
This study shows that a medicine called nedocromil can help kids with asthma feel better when the weather changes.
Methodology
A randomized, placebo-controlled, double-blind study with children receiving either nedocromil sodium or placebo for 6 weeks.
Limitations
The study had a small sample size and a relatively short duration.
Participant Demographics
Children aged 7-17 years, living in Milan, with episodic asthma and negative for perennial allergens.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
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