HIV-Associated Venous Thromboembolism

publication Evidence: moderate

Author Information

Author(s): Michele Bibas, Gianluigi Biava, Andrea Antinori

Primary Institution: National Institute for Infectious Diseases “Lazzaro Spallanzani”, IRCCS, Rome, Italy

Is HIV infection associated with an increased risk of venous thromboembolism (VTE)?

Chronic HIV infection is associated with a two to tenfold increased risk of venous thrombosis compared to the general population.

HIV infection has a reported VTE frequency ranging from 0.19% to 7.63% per year.
Patients with low CD4+ cell counts are at a higher risk for VTE.
Intravenous drug use significantly increases the risk of VTE in HIV-infected patients.

People with HIV are more likely to get blood clots than those without HIV, especially if they have low immune cell counts or other health issues.

Many studies were limited by small sample sizes and lack of population-based comparison controls.

HIV-infected individuals, with a median age of 40 at the time of VTE.

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