Surgical Versus Conservative Management of Delayed Presentation of Acute Biliary Disease: A Systematic Literature Review
2024

Surgical vs Conservative Management of Biliary Disease

Sample size: 14 publication 10 minutes Evidence: moderate

Author Information

Author(s): Muacevic Alexander, Adler John R, Khalifa Ahmad, Allami Sajad J, Tahhan Owais, Alhaj Shaikha S, Al Tahan Mohamad A, Elnogoomi Ibrahim

Hypothesis

What are the long-term outcomes of biliary sepsis in patients undergoing cholecystectomy compared to conservative management?

Conclusion

Cholecystectomy shows favorable long-term effects in managing biliary sepsis compared to conservative management.

Supporting Evidence

  • Early laparoscopic cholecystectomy significantly reduced hospital stays compared to delayed laparoscopic cholecystectomy.
  • Endoscopic sphincterotomy showed a 94% success rate in stone removal, reducing the need for emergency cholecystectomy.
  • Combined endoscopic-laparoscopic techniques had high success rates for stone removal without increasing complications.
  • Conservative management may lead to recurrent symptoms and complications, necessitating surgery later.

Takeaway

This study looks at how surgery and non-surgery help people with biliary problems, finding that surgery usually works better.

Methodology

A systematic review of literature from PubMed and Cochrane Library, including studies on surgical and conservative interventions for biliary sepsis.

Potential Biases

Potential publication bias due to the exclusion of non-English studies.

Limitations

Heterogeneity among included studies and reliance on individual study analysis may limit generalizability.

Participant Demographics

Included studies varied in demographics, focusing on adult populations with biliary sepsis.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.7759/cureus.74237

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