Crystal Structure of N-Cyclohexyl-2-(5-methoxy-1H-indol-3-yl)-2-oxoacetamide
Author Information
Author(s): Liu Jing, Liu Yong-Feng, Zhang Shi, Gao Ying, Chen Hong
Primary Institution: Tianjin Medical University
Hypothesis
The study aims to synthesize and report the crystal structure of a new indole derivative with potential biological activities.
Conclusion
The synthesized compound exhibits a crystal structure where the cyclohexane ring adopts a chair conformation and intermolecular hydrogen bonds link the molecules into layers.
Supporting Evidence
- The cyclohexane ring adopts a chair conformation.
- Intermolecular N—H⋯O hydrogen bonds link the molecules into layers.
Takeaway
The researchers made a new chemical compound and found that its structure is stable and organized in layers, which might help in its biological activities.
Methodology
The compound was synthesized through a two-step reaction involving oxalyl chloride and 5-methoxy-indole, followed by crystallization.
Digital Object Identifier (DOI)
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