Study of Phenolic Profiles and Bioactivities in Three Onosma Species
Author Information
Author(s): Panou Evgenia, Zengin Gokhan, Milic Nikola, Ganos Christos, Graikou Konstantia, Chinou Ioanna
Primary Institution: National & Kapodistrian University of Athens
Hypothesis
This study aims to evaluate and compare the phenolic profiles and bioactivities of three Onosma species.
Conclusion
The study found that Onosma leptantha had the highest total phenolic content and antioxidant activity, while Onosma graeca exhibited the highest total flavonoid content and enzyme inhibition.
Supporting Evidence
- Onosma leptantha showed a high total phenolic content of 69.03 mg GAE/g extract.
- Onosma graeca exhibited the highest total flavonoid content of 45.80 mg RE/g extract.
- All extracts demonstrated stronger AChE inhibition than BChE.
- OL was the most active against both α-glucosidase and α-amylase.
Takeaway
Researchers looked at three types of Onosma plants to see what good stuff they have inside and how they can help with health. They found that one type is really good at fighting off bad stuff in the body.
Methodology
The study used methanolic extracts of the aerial parts of three Onosma species, analyzed using UPLC-HRMS and various biological assays to evaluate antioxidant capacity and enzyme inhibition.
Limitations
The study focused only on the aerial parts of the plants and did not explore other parts or environmental factors affecting the phenolic profiles.
Statistical Information
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website