3D Printed Bigel: A Novel Delivery System for Cannabidiol-Rich Hemp Extract
2024

3D Printed Bigel: A Novel Delivery System for Cannabidiol-Rich Hemp Extract

publication Evidence: moderate

Author Information

Author(s): Gościniak Anna, Kocaj Filip, Stasiłowicz-Krzemień Anna, Szymański Marcin, Karpiński Tomasz M., Cielecka-Piontek Judyta

Primary Institution: Department of Pharmacognosy and Biomaterials, Poznan University of Medical Sciences

Hypothesis

The study aims to develop a novel bigel-based drug delivery system containing hemp extract to enhance the delivery of cannabinoids.

Conclusion

The 3D-printed bigel formulation significantly improves the delivery of cannabis extracts, offering a more convenient and effective therapeutic option for patients.

Supporting Evidence

  • The bigel formulation showed a release profile of CBD and CBDA ranging from 74.84% to 80.87% for CBD and from 80.84% to 98.31% for CBDA.
  • The study highlights the potential of bigels as a versatile delivery system for cannabinoids.
  • 3D printing technology allows for the customization of drug formulations tailored to individual patient needs.

Takeaway

Researchers created a new way to deliver cannabis medicine using a special gel that can be printed in 3D, making it easier for patients to take their medicine.

Methodology

The study involved developing a bigel formulation using 3D printing technology, incorporating cannabidiol-rich hemp extract, hyaluronic acid, and menthol.

Digital Object Identifier (DOI)

10.3390/gels10120770

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