Aerial Dissemination of Clostridium difficile spores
2008

Aerial Dissemination of Clostridium difficile Spores

Sample size: 23 publication Evidence: moderate

Author Information

Author(s): Katherine Roberts, Caroline F. Smith, Anna M. Snelling, Kevin G. Kerr, Kathleen R. Banfield, P. Andrew Sleigh, Clive B. Beggs

Primary Institution: University of Leeds

Hypothesis

Can Clostridium difficile be cultured from the air in a hospital setting?

Conclusion

The study found evidence of sporadic aerial dissemination of C. difficile spores, suggesting that current control measures may be inadequate.

Supporting Evidence

  • C. difficile was cultured from the air on two separate days.
  • Mean counts of C. difficile were between 53 and 426 cfu/m3 of air.
  • 22 out of 23 isolates belonged to ribotype 001.

Takeaway

The researchers found that tiny particles of a germ called C. difficile can float in the air in hospitals, which might help explain why some people keep getting sick.

Methodology

Air samples were collected using a portable cyclone sampler and surface samples using contact plates in a hospital ward.

Limitations

The study was a short pilot and did not yield C. difficile from environmental samples despite finding it in the air.

Participant Demographics

Elderly patients in a healthcare facility.

Digital Object Identifier (DOI)

10.1186/1471-2334-8-7

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