A case of massive hemoptysis caused by immunoglobulin G4-related respiratory disease in adults: case report and review of literature
2024

Massive Hemoptysis Caused by IgG4-Related Respiratory Disease: A Case Report

Sample size: 1 publication Evidence: low

Author Information

Author(s): Mei Chun-xia, Yue Guo-long, Feng Xia, Wu Hai-qiao, Li Jiong

Primary Institution: Department of Respiratory, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, China

Hypothesis

Can massive hemoptysis occur in adults with IgG4-related respiratory disease?

Conclusion

The case highlights the importance of early diagnosis and treatment of IgG4-related respiratory disease to improve patient prognosis.

Supporting Evidence

  • Only one case of massive hemoptysis in pediatric IgG4-RD has been described, with no adult cases reported prior to this.
  • The patient was treated with prednisone and leflunomide, which controlled her condition.
  • After 13 months without hemoptysis, the patient experienced intermittent hemoptysis followed by a massive episode.

Takeaway

This study talks about an 84-year-old woman who had a rare condition that made her cough up a lot of blood, but doctors were able to help her feel better with medicine.

Methodology

The authors presented a case report and conducted a literature review on IgG4-related disease involving hemoptysis.

Limitations

The study is based on a single case report, which may limit the generalizability of the findings.

Participant Demographics

An 84-year-old female patient.

Digital Object Identifier (DOI)

10.3389/fimmu.2024.1432508

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