An Automated Method for Rapid Identification of Putative Gene Family Members in Plants
2006

Automated Method for Identifying Gene Family Members in Plants

publication Evidence: moderate

Author Information

Author(s): Frank Ronald L, Mane Ajay, Ercal Fikret

Primary Institution: University of Missouri-Rolla

Hypothesis

Can we simplify the identification of gene family members in plants using automated software tools?

Conclusion

Gene families in plants can be quickly identified using integrated software tools and EST databases.

Supporting Evidence

  • The software tools correctly identified 3 of 4 known gene family members from Arabidopsis.
  • Two previously unidentified gene families in Glycine max were identified using the method.
  • The method simplifies the process of gene family identification by condensing multiple steps into fewer scripts.

Takeaway

This study shows that we can use special computer programs to find related genes in plants much faster than before.

Methodology

The study developed software tools to automate the identification of gene family members from EST data.

Limitations

The method may not identify all members of a gene family and relies on the quality of the EST database.

Statistical Information

P-Value

p<0.00001

Statistical Significance

p<0.00001

Digital Object Identifier (DOI)

10.1186/1471-2105-7-S2-S19

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