A Pilot Study to Evaluate the Minimally Invasive Burn Care for Small, Deep Partial-Thickness Burns of the Hands and Feet Using Enzyme Debridement and Autologous Skin Cell Spray
2024

Minimally Invasive Burn Care for Small Burns

Sample size: 4 publication Evidence: low

Author Information

Author(s): Aoki Kohei, Komiya Takako, Yamashita Kento, Shimada Kazuki, Fujii Miki, Matsumura Hajime

Primary Institution: Tokyo Medical University

Hypothesis

Can a combination of NexoBrid and ReCell techniques effectively treat deep partial-thickness burns of the hands and feet without conventional skin grafting?

Conclusion

The combination of NexoBrid and ReCell techniques resulted in early wound closure and good cosmetic outcomes for small burn wounds.

Supporting Evidence

  • All patients were satisfied with the aesthetic appearance of their hands and feet.
  • No complications, such as hypertrophic scars, were observed.
  • The mean Vancouver Scar Scale score was 0.25, indicating good scar quality.
  • Patients were followed up for an average of 12 months.

Takeaway

This study shows that using special treatments for small burns can help heal them quickly and make them look nice without needing a big skin graft.

Methodology

Four patients with deep partial-thickness burns were treated using NexoBrid for debridement followed by ReCell for skin regeneration.

Limitations

The study is a pilot and requires further research to confirm findings.

Participant Demographics

Patients aged 0–28 years with an average total burn surface area of 1.2%.

Digital Object Identifier (DOI)

10.3390/jcm13247721

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