Effects of Mucopolysaccharide Polysulphate on Skin Hydration and Elasticity
Author Information
Author(s): Wanitphakdeedecha Rungsima, Eimpunth Sasima, Manuskiatti Woraphong
Primary Institution: Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University
Hypothesis
Does 0.1% Mucopolysaccharide Polysulphate improve hydration and elasticity of human skin?
Conclusion
MPS improved skin hydration but not elasticity in women with dry skin compared to vehicle control.
Supporting Evidence
- 57 subjects completed the treatment protocol.
- Skin hydration significantly improved in the MPS group after 4 weeks.
- Skin elasticity improved in both groups, but no significant difference was found between MPS and control.
Takeaway
This study found that a cream with MPS helps keep skin hydrated for a long time, but it doesn't make skin more elastic.
Methodology
A randomized double-blind placebo-controlled study with 60 female volunteers applying either MPS or a control cream for 4 weeks.
Potential Biases
Potential bias due to the double-blind design, but both groups were treated identically.
Limitations
The study only included female participants aged 30-45 with dry skin, limiting generalizability.
Participant Demographics
60 female volunteers aged 30-45 with dry skin.
Statistical Information
P-Value
0.01
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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