Hantavirus Variant Found in Rodents in Russia
Author Information
Author(s): Lyudmila Yashina, Vasiliy Mishin, Nina Zdanovskaya, Connie Schmaljohn, Leonid Ivanov
Primary Institution: State Research Center of Virology and Biotechnology 'Vector'
Hypothesis
Whether pathogenic AMR genotype of virus exists in A. peninsulae throughout far eastern Asia requires further study.
Conclusion
The study provides the first genetic evidence for the AMR genotype of HTNV in A. peninsulae, suggesting this rodent species may be a natural reservoir for the pathogenic hantavirus.
Supporting Evidence
- Serologic studies suggest numerous hantaviruses are present in humans and rodents in far eastern Russia.
- Samples from four hantavirus-positive rodents were genetically characterized.
- The nucleotide sequence of the hantavirus detected in A. peninsulae diverged substantially from other hantaviruses.
Takeaway
Scientists found a new type of hantavirus in a type of mouse in Russia, which could make people sick.
Methodology
Lung-tissue samples from rodents were screened for hantavirus antigens and tested by PCR.
Limitations
The study does not confirm the pathogenicity of the AMR genotype in A. peninsulae across all of far eastern Asia.
Participant Demographics
Rodents captured in the far east of Russia.
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