Pathology and VP2-Based Characterization of Infectious Bursal Disease Virus Associated with an Outbreak in Layer Chickens in Ghana
2024

Characterization of Infectious Bursal Disease Virus in Layer Chickens in Ghana

Sample size: 8 publication Evidence: high

Author Information

Author(s): Enyetornye Ben, Abugri Henry A., Kusi-Appiah Ama K., Maboni Grazieli, Odoom Theophilus, Gottdenker Nicole L., Velayudhan Binu T.

Primary Institution: University of Georgia

Hypothesis

What is the molecular characterization of the infectious bursal disease virus (IBDV) strain associated with an outbreak in layer chickens in Ghana?

Conclusion

The study identified a very virulent strain of IBDV in layer chickens in Ghana, which is genetically similar to strains found in Nigeria.

Supporting Evidence

  • The IBDV strain was found to be closely related to Nigerian strains.
  • Mortality rates in the affected flock were reported at 0.3% and 3.7% on consecutive days.
  • This is the first report of IBDV sequencing from Ghana.
  • The study highlights the importance of biosecurity in poultry farming.
  • Vaccination may not have provided full protection against the outbreak.

Takeaway

This study looked at sick chickens in Ghana and found a bad virus that makes them very sick, which is similar to a virus found in Nigeria.

Methodology

The study involved post-mortem evaluations, histopathological examinations, RT-PCR, and phylogenetic analysis of IBDV.

Limitations

The characterization was solely based on the VP2 gene.

Participant Demographics

The study focused on a White Leghorn layer flock in Ghana.

Digital Object Identifier (DOI)

10.3390/pathogens13121115

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