The Many Forms and Functions of Long Term Plasticity at GABAergic Synapses
2011
The Many Forms and Functions of Long Term Plasticity at GABAergic Synapses
publication
Evidence: moderate
Author Information
Author(s): Arianna Maffei
Primary Institution: State University of New York (SUNY)
Hypothesis
How does plasticity at GABAergic synapses contribute to circuit function?
Conclusion
Inhibitory synaptic plasticity plays a crucial role in shaping the excitability and dynamic range of neural circuits.
Supporting Evidence
- Inhibitory synaptic transmission is crucial for the development and stability of neural circuits.
- Inhibitory synapses are plastic and can change their strength based on activity.
- Different forms of inhibitory plasticity contribute to the refinement of neural circuits.
Takeaway
This study shows that the connections in our brain can change over time, especially the ones that help calm down the activity of other brain cells.
Methodology
The article reviews recent findings on GABAergic synaptic plasticity and discusses its implications for neural circuit function.
Digital Object Identifier (DOI)
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