Automated Processing of Blood Samples into Plasma
Author Information
Author(s): C. A. Burtis, W. F. Johnson, W. A. Walker
Primary Institution: Oak Ridge National Laboratory
Hypothesis
The new rotor design can efficiently process a bulk aliquot of whole blood into multiple microliter aliquots of plasma.
Conclusion
The CPA-2 can produce multiple plasma aliquots with precision and accuracy comparable to mechanical pipettes.
Supporting Evidence
- The CPA-2 can produce discrete, microliter volumes of plasma with accuracy similar to mechanical pipettes.
- Capillary tubes used in the CPA-2 were capable of delivering microliter volumes with precision.
- Different capillary volumes can be selected for specific chemical assays.
Takeaway
This study shows a new machine that can quickly turn a big drop of blood into many tiny drops of plasma for testing.
Methodology
The CPA-2 rotor processes a bulk aliquot of blood into multiple plasma aliquots using centrifugal force and capillary action.
Limitations
The device is limited to producing a batch of single aliquots from single aliquots of whole blood.
Participant Demographics
Blood samples were collected from healthy subjects.
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