Nausea and Psychological Effects in Chemotherapy Patients
Author Information
Author(s): M. Watson, J. McCarron, M. Law
Primary Institution: Royal Marsden Hospital
Hypothesis
What is the prevalence of anticipatory nausea and emesis among out-patients on mild to moderate chemotherapy regimens?
Conclusion
The study found that 23% of patients experienced anticipatory nausea, which was linked to younger age and the emetic challenge of chemotherapy.
Supporting Evidence
- 73% of patients experienced post-treatment nausea during preceding cycles.
- 20% of all patients surveyed experienced anticipatory nausea before at least half of their preceding infusions.
- Anxiety levels were significantly higher in patients experiencing anticipatory symptoms.
Takeaway
Some cancer patients feel sick before their treatment even starts, and this can be linked to their age and how strong their medicine is.
Methodology
Patients completed an evaluation of nausea and emesis using the Morrow Assessment of Nausea and Emesis and the Hospital Anxiety and Depression scale.
Potential Biases
Potential pre-existing differences between groups may influence results.
Limitations
The study did not evaluate the role of anxiety in the aetiology of anticipatory nausea and emesis.
Participant Demographics
Mean age was 50 years, with a 2:1 female to male ratio.
Statistical Information
P-Value
0.003
Statistical Significance
p<0.05
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