Vaginal Inflammatory Status in Pregnant Women
Author Information
Author(s): Galiñanes Sebastián, Coppolillo Enrique, Cifarelli Maximiliano, Cora Eliseht Martha, Pellisa Ercilia, Losada Mirta, Gruccio Sebastián, Ruda Vega Hilda, Vay Carlos, Famiglietti Angela, Perazzi Beatriz
Primary Institution: Hospital de Clínicas, University of Buenos Aires
Hypothesis
The study aims to assess the vaginal inflammatory status in pregnant women by leukocyte quantification in relation to microbiota during each pregnancy trimester.
Conclusion
The vaginal inflammatory status is influenced by vaginal microbiota and depends on the state of pregnancy and gestational age.
Supporting Evidence
- Statistically significant differences in leukocyte counts were observed between symptomatic and asymptomatic patients.
- The study found that leukocyte counts increased with gestational age in asymptomatic patients.
- Patients with candidiasis showed significant differences in leukocyte counts compared to those without symptoms.
- No significant differences were found in leukocyte counts for patients with bacterial vaginosis.
Takeaway
This study looked at how the inflammation in the vagina of pregnant women changes based on their microbiota and pregnancy stage.
Methodology
The study involved examining vaginal exudates from pregnant women and quantifying leukocytes using May-Grunwald Giemsa staining.
Limitations
The study excluded patients with cervicitis, which may limit the generalizability of the findings.
Participant Demographics
Pregnant women examined at the Obstetrics Clinic at Hospital de Clínicas, University of Buenos Aires.
Statistical Information
P-Value
0.03
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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