Survival Factors in Metastatic Papillary Thyroid Cancer
Author Information
Author(s): Chrisoulidou Alexandra, Boudina Maria, Tzemailas Athanasios, Doumala Eleni, Iliadou Pashalia K, Patakiouta Frideriki, Pazaitou-Panayiotou Kalliopi
Primary Institution: Theagenio Cancer Hospital, Thessaloniki, Greece
Hypothesis
Histological subtype is the most important determinant of survival in metastatic papillary thyroid cancer.
Conclusion
Patients with aggressive variants of papillary thyroid cancer are at a higher risk for developing metastatic disease and should receive prompt treatment.
Supporting Evidence
- Histological subtype was the most important determinant of survival.
- Classic papillary thyroid cancer showed improved survival compared to other subtypes.
- The risk of death for non-classic subtypes was 4.56 times higher than for classic papillary type.
- Overall 10-year survival rate was 76.6% for patients with metastatic papillary thyroid cancer.
Takeaway
This study found that the type of papillary thyroid cancer affects how long patients live after it spreads, with some types being much worse than others.
Methodology
Retrospective review of 52 patients with metastatic papillary thyroid cancer over 20 years.
Potential Biases
Potential selection bias due to the retrospective design.
Limitations
The study is limited by its retrospective nature and small sample size.
Participant Demographics
29 females and 23 males, with a majority over 45 years of age.
Statistical Information
P-Value
0.004
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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