Depression and body mass index, a u-shaped association
2009

The Link Between Depression and Body Weight

Sample size: 43534 publication Evidence: high

Author Information

Author(s): de Wit Leonore M, van Straten Annemieke, van Herten Marieke, Penninx Brenda WJH, Cuijpers Pim

Primary Institution: VU University Amsterdam

Hypothesis

Is there a U-shaped association between Body Mass Index (BMI) and depression?

Conclusion

The study found a significant U-shaped trend indicating that both underweight and obesity are associated with higher levels of depression.

Supporting Evidence

  • The study found a very significant U-shaped association between BMI categories and depression.
  • A significant difference in the association between males and females was indicated.
  • Continuous BMI was not linearly associated with depression.

Takeaway

People who are either very thin or very heavy are more likely to feel sad than those who have a normal weight.

Methodology

The study used a cross-sectional design with a sample of 43,534 individuals, analyzing the relationship between BMI categories and depression using ANOVA and regression statistics.

Potential Biases

Self-reported data may lead to underestimation of weight and overestimation of height, potentially affecting the results.

Limitations

The study relied on self-reported data for BMI and had a significant number of missing values for both BMI and depression scores.

Participant Demographics

Participants were aged between 18 and 90 years, with a balanced representation of genders.

Statistical Information

P-Value

p ≤ 0.001

Statistical Significance

p ≤ 0.001

Digital Object Identifier (DOI)

10.1186/1471-2458-9-14

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