Thromboprophylaxis in Indian Patients with Major Orthopedic Trauma
Author Information
Author(s): Ramesh Kumar Sen, Sujit K Singh, Amit K
Primary Institution: Postgraduate Institute of Medical Education and Research, Chandigarh, India
Hypothesis
Is routine thromboprophylaxis justified among Indian patients sustaining major orthopedic trauma?
Conclusion
Routine thromboprophylaxis using LMWH is recommended for Indian patients after major orthopedic trauma to reduce the risk of venous thromboembolism.
Supporting Evidence
- Venous thromboembolism is a common preventable cause of morbidity and mortality after trauma.
- Incidence of VTE was found to be 14.49% in patients not receiving prophylaxis compared to 8% in those receiving it.
- Most studies recommended thromboprophylaxis in posttraumatic conditions in the Indian population.
Takeaway
This study says that Indian patients who have major injuries need medicine to prevent blood clots, which can be dangerous.
Methodology
A systematic review of 10 studies on venous thromboembolism in Indian patients after major orthopedic trauma.
Potential Biases
The reluctance among Indian surgeons to provide thromboprophylaxis may lead to underestimation of the risk of VTE.
Limitations
The review is based on studies that lack multicentric and randomized control trials.
Participant Demographics
Indian patients with major orthopedic trauma.
Digital Object Identifier (DOI)
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