Rosai-Dorfman Disease: A previously unreported association with Sickle Cell Disease
2007
Rosai-Dorfman Disease and Sickle Cell Disease in a Child
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Claire Stebbing, Jon van der Walt, Ghada Ramadan, Baba Inusa
Primary Institution: Guy's and St Thomas' Hospital, London, UK
Conclusion
This case presents the first documented occurrence of Rosai-Dorfman Disease in a child with Sickle Cell Disease.
Supporting Evidence
- The child was diagnosed with Sickle Cell Anemia at birth.
- Massive lymphadenopathy was noted during routine check-ups.
- A biopsy confirmed the diagnosis of Rosai-Dorfman Disease.
- The child experienced complications from Sickle Cell Disease, including cardiomyopathy.
Takeaway
A boy with Sickle Cell Disease also had a rare condition called Rosai-Dorfman Disease, which caused swollen lymph nodes.
Methodology
Case report detailing the medical history and clinical findings of a child diagnosed with both diseases.
Limitations
The case is based on a single patient, limiting generalizability.
Participant Demographics
A three-year-old Nigerian boy.
Digital Object Identifier (DOI)
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