SARS-CoV-2 Immunization Index in the Academic Community
Author Information
Author(s): Keltyn Oliveira, Ana Almeida, Carina Silva, Miguel Brito, Edna Ribeiro, Nicola Petrosillo
Primary Institution: Instituto Politécnico de Lisboa
Hypothesis
This study aimed to estimate the positivity and levels of SARS-CoV-2 IgG antibodies acquired due to vaccination and infection in the academic population of a Portuguese university.
Conclusion
The study found that vaccination effectiveness and group immunity assessment are crucial for managing the pandemic, particularly in academic environments.
Supporting Evidence
- 529 volunteers with at least one dose of the vaccine were enrolled in this study.
- Data analysis showed a higher level of IgG against SARS-CoV-2 in individuals who were younger and female.
- Individuals who received a mixed booster dose had higher antibody levels compared to those who received the same vaccine for the booster.
Takeaway
This study looked at how well COVID-19 vaccines work in a university, finding that younger people and women had higher antibody levels after vaccination.
Methodology
Blood samples were collected and analyzed through the ELISA methodology, and statistical analysis was performed.
Potential Biases
Potential biases may arise from self-selection of participants and the retrospective nature of the study.
Limitations
The study may not account for all factors influencing antibody levels, and the sample was limited to one academic institution.
Participant Demographics
Participants included students, professors, and staff aged 17 to 76 years, with 68% being female.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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