RGST - Rat Gene Symbol Tracker, a database for defining official rat gene symbols
2008

Rat Gene Symbol Tracker: A Database for Rat Gene Symbols

publication Evidence: high

Author Information

Author(s): Greta Petersen, Fredrik Ståhl

Primary Institution: Göteborgs Universitet

Hypothesis

There is a need for a cohesive and unifying overview of all rat gene symbols in use.

Conclusion

The RGST database successfully unifies rat gene symbols into an automatic and cohesive nomenclature system.

Supporting Evidence

  • The database compares rat gene symbols with human orthologs to ensure accuracy.
  • RGST automatically implements major rat gene symbol nomenclature rules.
  • Approximately 12,000 rat genes have been given contradictory symbols from different sources.

Takeaway

This study created a database that helps scientists find the correct names for rat genes, making it easier to understand their functions.

Methodology

The RGST database integrates gene data from multiple sources and applies rat gene symbol nomenclature rules to assign conclusive gene symbols.

Limitations

The database relies on existing data from other sources, which may contain inconsistencies.

Digital Object Identifier (DOI)

10.1186/1471-2164-9-29

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