Altered Rhythmicity, Depressive Ruminative Thinking and Suicidal Ideation as Possible Correlates of an Unrecognized Autism Spectrum in Patients with Borderline Personality Disorder
2024

Autistic Traits and Their Impact on Borderline Personality Disorder

Sample size: 48 publication 10 minutes Evidence: moderate

Author Information

Author(s): Cremone Ivan Mirko, Dell’Osso Liliana, Nardi Benedetta, Giovannoni Federico, Parri Francesca, Pronestì Cristiana, Bonelli Chiara, Massimetti Gabriele, Pini Stefano, Carpita Barbara

Primary Institution: Department of Clinical and Experimental Medicine, University of Pisa, Italy

Hypothesis

This study aims to investigate the relationship between autistic traits and affective symptoms, including mood instability and suicidality, in people diagnosed with borderline personality disorder.

Conclusion

The study confirms a relationship between clinically significant autistic traits and increased affective symptoms, ruminative thinking, and suicidality in patients with borderline personality disorder.

Supporting Evidence

  • Subjects with significant autistic traits scored higher in all domains of the AdAS Spectrum, RRS, and MOODS-SR.
  • Ruminative response scale total score was a significant predictor of the presence of clinically relevant autistic traits.
  • Suicidal ideation was identified as a significant predictor of the presence of significant autistic traits.
  • Patients with borderline personality disorder and autistic traits showed higher levels of mood instability and impulsivity.

Takeaway

People with borderline personality disorder who also have autistic traits may feel sadder and think about suicide more often.

Methodology

The study assessed 48 patients with borderline personality disorder using self-report questionnaires to evaluate autistic traits, mood symptoms, and ruminative thinking.

Potential Biases

Potential selection bias due to the recruitment process and the presence of depressive or anxiety symptoms in some participants.

Limitations

The cross-sectional design limits causal conclusions, and self-report measures may introduce bias.

Participant Demographics

The sample consisted of patients diagnosed with borderline personality disorder, with no significant differences in age or gender between groups.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/brainsci14121297

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