Colonic Involvement in a Patient with Chronic Lymphocytic Leukaemia
Author Information
Author(s): Arkkila P. E. T., Nuutinen H., Ebeling F., Elonen E., Kärkkäinen P., Karjalainen-Lindsberg M.-L.
Primary Institution: Helsinki University Central Hospital
Hypothesis
Can gastrointestinal manifestations occur in patients with chronic lymphocytic leukaemia (CLL) even when there are no macroscopic signs?
Conclusion
The study found that a patient with CLL had histological evidence of gastrointestinal involvement despite normal macroscopic findings.
Supporting Evidence
- The patient had normal macroscopic findings during colonoscopy but histological evidence of CLL.
- Endoscopies are necessary for CLL patients with unexplained gastrointestinal symptoms or anaemia.
- Histological examination revealed lymphocytic infiltration in the ileum and colon.
Takeaway
This study shows that even if a patient with CLL looks fine on the outside, they might still have problems inside their gut that need checking.
Methodology
The patient underwent gastrointestinal endoscopies and biopsies to assess for gastrointestinal involvement of CLL.
Limitations
The findings are based on a single case report, which may not be generalizable.
Participant Demographics
69-year-old male, ex-smoker, with chronic atrial fibrillation.
Digital Object Identifier (DOI)
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