Validation of a Sensor for Screening Sleep Apnea in Heart Failure Patients
Author Information
Author(s): Barbieri Fabian, Adukauskaite Agne, Spitaler Philipp, Senoner Thomas, Pfeifer Bernhard, Neururer Sabrina, Jacon Peggy, Venier Sandrine, Limon Sarah, Ben Messaoud Raoua, Pépin Jean-Louis, Hintringer Florian, Dichtl Wolfgang, Defaye Pascal
Primary Institution: Department of Cardiology, Angiology and Intensive Care, Deutsches Herzzentrum der Charité, Berlin, Germany
Hypothesis
Can the AP scan® sensor accurately screen for sleep apnea in heart failure patients compared to polysomnography?
Conclusion
The AP scan® sensor correlates well with polysomnography-derived apnea-hypopnea index in heart failure patients, particularly in those with obstructive sleep apnea.
Supporting Evidence
- The AP scan® correlated significantly with the AHI (r = 0.61, p < 0.001).
- Median AHI was 21.6 events/h, while median AP scan® was 33.0 events/h.
- The AP scan® performed well in females (r = 0.71, p = 0.047).
- Strong correlation was observed in OSA patients (r = 0.73, p = 0.011).
- No correlation was found in patients suffering from CSA (r = 0.28, p = 0.348).
- Taking multiple measurements did not improve diagnostic accuracy.
- 58.8% of participants were obese, which may affect sleep apnea severity.
- Overall, 67.5% of patients received an upgrade to a CRT system.
Takeaway
Doctors used a special sensor to check if heart failure patients have sleep apnea, and it worked pretty well compared to the best tests.
Methodology
The study pooled data from two trials, AIRLESS and UPGRADE, to validate the AP scan® against polysomnography in heart failure patients.
Potential Biases
Potential bias due to the small number of participants and differences in inclusion criteria between the two trials.
Limitations
The study had a small sample size and included only heart failure patients, which may limit the generalizability of the findings.
Participant Demographics
Majority were male (83.8%) with a median age of 73 years; 58.8% were obese.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI −38.2 to 13.0
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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