Design and dosimetric characterization of a transportable proton minibeam collimation system
2024

Transportable Proton Minibeam System Development

publication Evidence: moderate

Author Information

Author(s): Ahmed Mabroor, Beyreuther Elke, Gantz Sebastian, Horst Felix, Meyer Juergen, Pawelke Jörg, Schmid Thomas E., Stolz Jessica, Wilkens Jan J., Bartzsch Stefan

Primary Institution: Helmholtz Zentrum München GmbH

Hypothesis

Can a mechanical collimation setup be developed to produce 250µm wide proton minibeams with a center-to-center distance of 1000µm?

Conclusion

The novel proton minibeam system can be operated independently of specific beamlines and is suitable for inter-institutional studies.

Supporting Evidence

  • A PVDR of 10 was achieved in Dresden and a PVDR of 14 in Seattle.
  • The microDiamond detector was shown to have potential for online dosimetry for proton minibeams.
  • Discrepancies in peak dose measurements highlight the need for further research on detector response.

Takeaway

Researchers created a new system to make tiny proton beams that can be easily moved and used in different places for experiments.

Methodology

Monte Carlo simulations were used to optimize the collimation setup, followed by experimental dosimetry at two proton therapy facilities.

Limitations

The microDiamond detector showed discrepancies in peak dose measurements compared to film dosimetry.

Digital Object Identifier (DOI)

10.3389/fonc.2024.1473625

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