Diagnostic difficulties of Lactobacillus casei bacteraemia in immunocompetent patients: A case report
2008

Lactobacillus casei Bacteraemia in an Immunocompetent Patient

Sample size: 1 publication Evidence: low

Author Information

Author(s): Tommasi Chiara, Equitani Francesco, Masala Marcello, Ballardini Milva, Favaro Marco, Meledandri Marcello, Fontana Carla, Narciso Pasquale, Nicastri Emanuele

Primary Institution: National Institute for Infectious Diseases, INMI 'L. Spallanzani'

Hypothesis

Can Lactobacillus casei cause serious infections in immunocompetent individuals?

Conclusion

Lactobacillus casei can cause bacteraemia in immunocompetent patients, which is often underestimated.

Supporting Evidence

  • Lactobacillus casei is usually considered a contaminant in blood cultures.
  • The patient had a history of consuming probiotic products.
  • 16S ribosomal RNA sequencing was used for accurate identification of the bacteria.

Takeaway

Sometimes, bacteria that are usually harmless can make people sick, even if they are healthy. This study shows that Lactobacillus casei can cause infections.

Methodology

The case study involved blood cultures and molecular identification using 16S ribosomal RNA sequencing.

Limitations

The study is based on a single case, which may not represent broader trends.

Participant Demographics

A 66-year-old immunocompetent male.

Digital Object Identifier (DOI)

10.1186/1752-1947-2-315

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