Cholestasis in Hyperthyroidism: Two Case Reports
Author Information
Author(s): Soylu Aliye, Taskale Mustafa Gurkan, Ciltas Aydin, Kalayci Mustafa, Kumbasar A Baki
Primary Institution: Dr Sadi Konuk Research Hospital, Istanbul, Turkey
Hypothesis
Can hyperthyroidism lead to intrahepatic cholestasis?
Conclusion
Hyperthyroidism should be a consideration in non-specific liver dysfunction.
Supporting Evidence
- Both patients had cholestasis linked to hyperthyroidism.
- One patient improved with rifampicin treatment.
- The other patient improved after radioactive iodine therapy.
Takeaway
Sometimes, when people have too much thyroid hormone, it can make their liver not work right, causing yellow skin and itching. Two patients showed this and got better with treatment.
Methodology
Case reports of two patients with cholestasis related to hyperthyroidism, detailing their symptoms, lab results, and treatment responses.
Limitations
The study is based on only two case reports, limiting generalizability.
Participant Demographics
One male aged 47 and one female aged 67.
Digital Object Identifier (DOI)
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