Coffee and Liver Cancer Risk in Japan
Author Information
Author(s): Kurozawa Y, Ogimoto I, Shibata A, Nose T, Yoshimura T, Suzuki H, Sakata R, Fujita Y, Ichikawa S, Iwai N, Tamakoshi A
Primary Institution: Tottori University
Hypothesis
Is there a relationship between coffee consumption and mortality from hepatocellular carcinoma (HCC)?
Conclusion
The study found that coffee consumption is associated with a reduced risk of death from HCC.
Supporting Evidence
- Coffee drinkers had a hazard ratio of 0.50 for HCC mortality compared to non-drinkers.
- The study included 110,688 participants from the Japan Collaborative Cohort Study.
- The results were adjusted for various confounding factors including age and smoking.
Takeaway
Drinking coffee might help people live longer if they have liver cancer.
Methodology
Cox proportional hazards model was used to analyze the relationship between coffee consumption and HCC mortality.
Limitations
The absence of serum markers for HCV or HBV infection is a major limitation.
Participant Demographics
Participants were aged 40-79 years, with 46,399 males and 64,289 females.
Statistical Information
P-Value
0.007
Confidence Interval
0.31–0.79
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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