New Methods for Making Dihydrobenzofurans
Author Information
Author(s): Mushtaq Aqsa, Irfan Muhammad, Haq Atta ul, Mansha Asim, Khan Samreen Gul, Ameer Fawad Zahoor, Parveen Bushra, Irfan Ali, Kotwica-Mojzych Katarzyna, Glowacka Mariola, Mojzych Mariusz
Primary Institution: Department of Chemistry, Government College University Faisalabad, Faisalabad, Pakistan
Conclusion
This review highlights recent advancements in transition metal-free synthetic methods for creating dihydrobenzofurans, emphasizing their significance in medicinal chemistry.
Supporting Evidence
- Dihydrobenzofurans are important in medicinal chemistry due to their presence in various biologically active compounds.
- Recent synthetic methods have improved yields and reduced the use of toxic metal catalysts.
- Transition metal-free approaches align with green chemistry principles, addressing environmental concerns.
Takeaway
Scientists have found new ways to make a special chemical structure called dihydrobenzofurans without using metals, which is better for the environment.
Methodology
This review summarizes various synthetic strategies developed from 2021 to 2023, including Bronsted acid-mediated, Lewis acid-induced, photocatalytic, base-catalyzed, iodine-promoted, electrocatalytic, and organocatalyzed methods.
Limitations
The review does not provide experimental data or specific quantitative results from the discussed methodologies.
Digital Object Identifier (DOI)
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