Occurrence and Antibiogram of Salmonella Typhi and S. Paratyphi A in Rourkela
Author Information
Author(s): Bhattacharya S, Das Usha, Choudhury B.K.
Primary Institution: Ispat General Hospital, Rourkela, India
Hypothesis
The study aims to investigate the incidence and antibiotic resistance patterns of Salmonella Typhi and S. Paratyphi A in Rourkela.
Conclusion
The study found a year-round occurrence of Salmonella spp. in Rourkela, with concerning trends of antibiotic resistance in S. Paratyphi A.
Supporting Evidence
- 298 Salmonella isolates were identified, showing an overall positivity rate of 5.58%.
- Multidrug resistance was found in 11.96% of S. Typhi and 15.62% of S. Paratyphi A isolates.
- Less than 2% of isolates showed resistance to ciprofloxacin.
- Resistance to third generation cephalosporins was observed in 3.0 to 6.25% of isolates.
Takeaway
The researchers looked at blood samples to see how often two types of germs that cause fever show up and how well medicines work against them.
Methodology
The study involved collecting and analyzing 5340 blood samples from patients suspected of having enteric fever over four years.
Potential Biases
Potential bias in sample selection as only patients with suspected enteric fever were included.
Limitations
The study may not account for all cases of enteric fever due to reliance on blood culture results.
Participant Demographics
64.23% of participants were children and 35.76% were adults, with a slight male predominance in both groups.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
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