Two genotypes of H3N2 swine influenza viruses identified in pigs from Shandong Province, China
2024

Two genotypes of H3N2 swine influenza viruses identified in pigs from Shandong Province, China

Sample size: 372 publication Evidence: high

Author Information

Author(s): Zhao Yuzhong, Han Lebin, Sang Haotian, Yang Pingping, Hou Yanmeng, Xiao Yihong

Primary Institution: Shandong Agricultural University

Hypothesis

This study aims to analyze the genetic and molecular characteristics of H3N2 swine influenza viruses in pigs.

Conclusion

The study identified two distinct genotypes of H3N2 swine influenza viruses, highlighting their potential zoonotic risk and the need for enhanced surveillance.

Supporting Evidence

  • Phylogenetic analysis revealed two distinct genotypes of H3N2 swine influenza viruses.
  • Homology analysis showed over 96% genetic similarity between the isolates and reference strains.
  • Key mutations in the virus proteins suggest potential for increased virulence and zoonotic risk.
  • Serological analysis indicated a low positivity rate for H3N2 antibodies among tested serum samples.

Takeaway

Scientists studied pig samples to find two types of a virus that can make pigs sick and might also make people sick.

Methodology

The study involved collecting nasal swabs, lungs, and trachea samples from pigs, followed by genetic and molecular analysis.

Limitations

The study was limited to samples collected from specific regions in Shandong Province and may not represent the entire population.

Participant Demographics

Samples were collected from pigs across eight regions in Shandong Province, China.

Digital Object Identifier (DOI)

10.3389/fcimb.2024.1517023

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