Survival rate in nasopharyngeal carcinoma improved by high caseload volume: a nationwide population-based study in Taiwan
2011

High Caseload Volume Improves Survival in Nasopharyngeal Carcinoma

Sample size: 1225 publication Evidence: high

Author Information

Author(s): Lee Ching-Chih, Huang Tze-Ta, Lee Moon-Sing, Su Yu-Chieh, Chou Pesus, Hsiao Shih-Hsuan, Chiou Wen-Yen, Lin Hon-Yi, Chien Sou-Hsin, Hung Shih-Kai

Primary Institution: Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan

Hypothesis

Is there a relationship between physician caseload and survival rates in nasopharyngeal carcinoma treatment?

Conclusion

Patients with nasopharyngeal carcinoma treated by high-volume physicians have better 10-year survival rates.

Supporting Evidence

  • Patients treated by high-volume physicians had a 10-year survival rate of 75%.
  • Patients treated by low/medium-volume physicians had a 10-year survival rate of 61%.
  • The study used a large population-based dataset from Taiwan's National Health Insurance Research Database.

Takeaway

If a doctor treats more patients with nasopharyngeal cancer, their patients are more likely to live longer.

Methodology

The study analyzed data from 1225 patients using survival analysis, Cox proportional hazards model, and propensity score.

Potential Biases

Potential selection bias due to the referral of healthier patients to high-volume physicians.

Limitations

The study could not assess the relationship of caseload to NPC stage due to lack of data.

Participant Demographics

Majority of patients were male (72%); included patients treated between 1998 and 2000.

Statistical Information

P-Value

p < 0.001

Confidence Interval

95% CI, 0.45-0.78

Statistical Significance

p < 0.001

Digital Object Identifier (DOI)

10.1186/1748-717X-6-92

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