Impact of Gender on Microvascular Obstruction After Heart Attack
Author Information
Author(s): de Waha Suzanne, Eitel Ingo, Desch Steffen, Fuernau Georg, Lurz Philipp, Grothoff Matthias, Gutberlet Matthias, Schuler Gerhard, Thiele Holger
Primary Institution: University of Leipzig – Heart Center
Hypothesis
The presence and extent of microvascular obstruction after ST-elevation myocardial infarction differ between genders.
Conclusion
Despite longer ischemic time and a more disadvantageous cardiovascular risk profile in women, the prevalence and extent of microvascular obstruction do not differ between genders.
Supporting Evidence
- Women were significantly older than men.
- Women had longer symptom-onset-to-reperfusion times.
- Women had a higher prevalence of diabetes mellitus and arterial hypertension.
- The prevalence and extent of microvascular obstruction were similar in both genders.
Takeaway
This study looked at how men and women are affected by heart attacks. Even though women had more health issues and longer wait times for treatment, both genders had similar problems with blood flow after the heart attack.
Methodology
Patients with ST-elevation myocardial infarction underwent contrast-enhanced MRI to measure microvascular obstruction.
Participant Demographics
105 women and 318 men, with women being older and having more cardiovascular risk factors.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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