Influences of Prenatal and Maternal Factors on Autism in Children
Author Information
Author(s): Abdelkader Ahmed, AlRadini Faten, Alosaimi Ashwaq, Abbas Abdallah, Judeh Zaki, Emy Abu Esaid Tahneed, Saleh Alaa, Shah Jaffer, Amer Samar
Primary Institution: Princess Nourah bint Abdulrahman University
Hypothesis
This study explores the potential causes of autism, including maternal and paternal prenatal risk factors, as well as antenatal and natal maternal risk factors, and their associations with the severity of ASD.
Conclusion
The study found significant associations between gestational diabetes and the severity of autism, highlighting the importance of monitoring maternal health during pregnancy.
Supporting Evidence
- 79.2% of children had maternal and/or paternal antenatal exposures.
- Gestational diabetes was a significant predictor of severe autism.
- Each year of the child's age increased the likelihood of severe autism by 7.1%.
Takeaway
Moms' health during pregnancy can affect how severe autism is in their kids, especially if they have conditions like diabetes.
Methodology
This cross-sectional study used a web-based survey with a structured questionnaire to gather data from mothers of children diagnosed with ASD.
Potential Biases
Recall bias may affect the accuracy of reported maternal health and lifestyle factors.
Limitations
The study's cross-sectional design may introduce recall biases, and it excluded mothers with complex medical, psychological, or mental disorders, which may affect generalizability.
Participant Demographics
The median maternal age was 30 years, and the median paternal age was 35 years, with most participants residing in urban areas.
Statistical Information
P-Value
0.047
Confidence Interval
[1.518, 14.25]
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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