Atypical Cerebral Carcinoids Treated with Hippocampal-Sparing Whole Brain Radiotherapy
2024

Hippocampal-Sparing Whole Brain Radiotherapy for Atypical Cerebral Carcinoids

Sample size: 1 publication Evidence: low

Author Information

Author(s): Muacevic Alexander, Adler John R, Knight James A II, Mourad Waleed F, Nebbache Hafsa, Kaushal Aradhana

Primary Institution: University of Kentucky

Hypothesis

Can hippocampal-sparing whole brain radiotherapy improve outcomes for patients with atypical cerebral carcinoids?

Conclusion

The case demonstrates that hippocampal-sparing whole brain radiotherapy can effectively control brain metastases while preserving cognitive function.

Supporting Evidence

  • The patient showed a decrease in the size and number of brain metastases after treatment.
  • She reported stable memory and cognition 11 months post-treatment.
  • The treatment was well-tolerated with minimal side effects.

Takeaway

This study shows that a special type of radiation therapy can help patients with rare brain tumors without hurting their memory.

Methodology

The patient received 30 Gy in 10 fractions of hippocampal-sparing whole brain radiotherapy using image-guided photon therapy.

Limitations

The study is based on a single case, limiting the generalizability of the findings.

Participant Demographics

A 62-year-old female patient with a history of stage IIB bronchopulmonary carcinoid.

Digital Object Identifier (DOI)

10.7759/cureus.74997

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