CT and Ultrasound Guided Biopsy for Non-Hodgkin's Lymphoma
Author Information
Author(s): J.S. Whelan, R.H. Reznek, S.J.N. Daniell, A.J. Norton, T.A. Lister, A.Z.S. Rohatiner
Primary Institution: St Bartholomew's Hospital, London
Hypothesis
Can core biopsy with CT or ultrasound guidance provide a reliable alternative to open biopsy in managing non-Hodgkin's lymphoma?
Conclusion
Core needle biopsy using the Biopty Gun is a safe and effective alternative to more invasive surgical procedures for managing non-Hodgkin's lymphoma.
Supporting Evidence
- Tissue samples were obtained at all 34 attempts with no complications.
- A primary histological diagnosis was made in 7 out of 7 patients with suspected lymphoma.
- Relapse was confirmed in 15 out of 15 patients overall.
- The procedure was well tolerated and required further procedures only on three occasions.
Takeaway
Doctors can use a special needle to take samples from deep lumps in the body without needing big surgeries, which helps them figure out how to treat cancer better.
Methodology
Thirty-four biopsies were performed in 26 patients using CT or ultrasound guidance to obtain tissue samples for diagnosis.
Limitations
The study primarily involved patients at relapse rather than at first presentation, which may limit generalizability.
Participant Demographics
Thirteen men and thirteen women with a median age of 50 years (range 30-86).
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