2-Methyl-5-[(3-methyl-4-nitrobenzyl)sulfanyl]-1,3,4-thiadiazole
2011
Crystal Structure of a Thiadiazole Derivative
publication
Evidence: moderate
Author Information
Author(s): Fun Hoong-Kun, Chantrapromma Suchada, Chandrakantha B., Isloor Arun M., Shetty Prakash
Primary Institution: Universiti Sains Malaysia
Hypothesis
The study aims to investigate the crystal structure and potential biological activity of a synthesized thiazole derivative.
Conclusion
The thiazole derivative exhibits a butterfly-like structure and is disordered over two sites.
Supporting Evidence
- The molecule has a butterfly-like structure.
- It is disordered with a site-occupancy ratio of 0.629:0.371.
- The dihedral angle between the thiazole and benzene rings is approximately 70.8°.
- Weak intermolecular interactions stabilize the crystal structure.
Takeaway
The researchers made a new chemical compound and looked at its structure using X-ray techniques to see how it might work in medicine.
Methodology
The compound was synthesized and its crystal structure was determined using X-ray crystallography.
Digital Object Identifier (DOI)
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