HBV Infection in Relation to Consistent Condom Use: A Population-Based Study in Peru
2011

Hepatitis B Virus Infection and Condom Use in Peru

Sample size: 7000 publication 10 minutes Evidence: moderate

Author Information

Author(s): Antonio Bernabe-Ortiz, Cesar P. Carcamo, John D. Scott, James P. Hughes, Patricia J. Garcia, King K. Holmes, Andres G. Lescano

Primary Institution: Universidad Peruana Cayetano Heredia

Hypothesis

What is the relationship between hepatitis B virus (HBV) infection and consistent condom use in young adults in Peru?

Conclusion

Consistent condom use is associated with a lower prevalence of hepatitis B virus infection among young adults in Peru.

Supporting Evidence

  • Anti-HBc prevalence was 5.0% overall, with higher rates in jungle cities at 16.3%.
  • Consistent condom use was associated with a lower prevalence of anti-HBc (2.6% vs 5.8% among never users).
  • Geographic region and age at sexual debut were significant factors associated with anti-HBc positivity.

Takeaway

This study found that using condoms all the time can help prevent hepatitis B infections, especially in areas where the virus is more common.

Methodology

Data from two cross-sectional surveys were analyzed, involving 7000 participants aged 18-29 years, using multistage cluster sampling and a validated questionnaire.

Potential Biases

Self-reported condom use may lead to recall bias or social desirability bias.

Limitations

The study did not include non-sexual risk factors for HBV and was limited to urban areas and young adults, which may not represent the entire population.

Participant Demographics

47.6% were men, mean age was 22.9 years, 57.3% had less than 12 years of education, and 64.2% were never married.

Statistical Information

P-Value

p<0.001

Confidence Interval

95%CI 4.1%–5.9%

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1371/journal.pone.0024721

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