Evolutionary origins and functional diversification of Auxin Response Factors
2024

Evolutionary origins and functional diversification of Auxin Response Factors

publication 10 minutes Evidence: high

Author Information

Author(s): Hernández-García Jorge, Carrillo-Carrasco Vanessa Polet, Rienstra Juriaan, Tanaka Keita, de Roij Martijn, Dipp-Álvarez Melissa, Freire-Ríos Alejandra, Crespo Isidro, Boer Roeland, van den Berg Willy A. M., Lindhoud Simon, Weijers Dolf

Primary Institution: Wageningen University

Hypothesis

It is unclear how Auxin Response Factors (ARFs) emerged, and how early diversification led to functionally different proteins.

Conclusion

The study reveals the shared origin of ARFs from preexisting domains and reconstructs their complete evolutionary history.

Supporting Evidence

  • The study reconstructs the complete evolutionary history of ARFs, including divergence events.
  • ARFs have diverged into three functionally different classes: A, B, and C.
  • Phylogenomic and genetic analysis provided insights into the origin and minimal architecture of the nuclear auxin response system.

Takeaway

Scientists studied how certain proteins that help plants respond to a hormone called auxin evolved over time, showing that they came from older proteins and changed to do different jobs.

Methodology

The study used in silico and in vivo analyses to investigate the molecular events leading to the origin and evolution of ARFs.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1038/s41467-024-55278-8

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