Thyroid Cancer Diagnosis Review in Belarus and Ukraine
Author Information
Author(s): Brigitte Franc, M Valenty, K Galakhin, E Kovalchuk, V Kulagenko, A Puchkou, Y Sidorov, M Tirmarche
Primary Institution: Hôpital Ambroise Paré, France
Hypothesis
The study aims to determine the reliability of epidemiological studies based on pathological reports without any histological review of malignant cases registered.
Conclusion
The study found that the agreement between initial diagnoses and final consensus diagnoses was high, indicating the reliability of cancer registries in Belarus and Ukraine.
Supporting Evidence
- The study reviewed 327 thyroid carcinoma cases to assess the reliability of initial diagnoses.
- Agreement between initial and final diagnoses was found in 93% of cases.
- Discrepancies persisted in only 2.8% of cases after review.
Takeaway
Doctors looked at old thyroid cancer samples from Belarus and Ukraine to see if the original diagnoses were correct, and they found that most of them were.
Methodology
The study involved reviewing pathology slides of thyroid carcinoma cases from cancer registries in Belarus and Ukraine, with a panel of six pathologists assessing the diagnoses.
Potential Biases
Potential bias due to reliance on initial pathology reports without prior review.
Limitations
Some cases were excluded from review due to poor quality or unavailability of slides.
Participant Demographics
The population consisted of 246 female and 81 male subjects, aged 15 to 82 years.
Statistical Information
P-Value
0.61
Confidence Interval
[0.45–0.77]
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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