Incidence of lower respiratory tract infections in patients treated with post-cardiac arrest mild therapeutic hypothermia and selective digestive tract decontamination
2011

Lower Respiratory Infections in Cardiac Arrest Patients Treated with Hypothermia

Sample size: 55 publication Evidence: low

Author Information

Author(s): Vellinga NA, Boerma EC, Kuiper MA

Primary Institution: Medisch Centrum Leeuwarden

Hypothesis

Does selective digestive tract decontamination reduce the incidence of lower respiratory tract infections in post-cardiac arrest patients treated with mild therapeutic hypothermia?

Conclusion

The study suggests that selective digestive tract decontamination may help prevent lower respiratory tract infections during mild therapeutic hypothermia treatment.

Supporting Evidence

  • 30.9% of patients in the study died in the hospital.
  • 59.5% of patients had a potentially pathogenic microorganism present in their sputum.
  • Candida albicans was the most prevalent microorganism found.
  • 24% of patients had a potentially pathogenic microorganism that required antibiotics.

Takeaway

Doctors looked at how to stop lung infections in patients who had a heart attack and were cooled down. They found that a special treatment helped keep these infections away.

Methodology

Sputum samples were collected from post-cardiac arrest patients treated with mild therapeutic hypothermia and selective digestive tract decontamination over a period of two years.

Limitations

The study had a small sample size and was conducted in a single center.

Participant Demographics

44 males and 11 females, all post-cardiac arrest patients.

Digital Object Identifier (DOI)

10.1186/cc9722

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