Alcohol Consumption and Renal Cell Cancer Risk
Author Information
Author(s): Lew J Q, Chow W-H, Hollenbeck A R, Schatzkin A, Park Y
Primary Institution: National Cancer Institute
Hypothesis
What is the relationship between alcohol consumption and the risk of renal cell cancer?
Conclusion
Alcohol consumption was inversely associated with renal cell cancer risk in a dose-response manner.
Supporting Evidence
- Men who drank 15 to <30 g of alcohol per day had a 25% lower risk of RCC compared to those who drank 0 to <5 g.
- Women who drank ≥30 g of alcohol per day had a 57% lower risk of RCC compared to those who drank 0 to <5 g.
- The study included a large cohort of over 492,000 participants.
- Alcohol consumption was assessed using a food frequency questionnaire.
- RCC cases were identified through state cancer registries.
Takeaway
Drinking alcohol might actually lower the risk of kidney cancer, especially if you drink more than a little bit.
Methodology
The study examined the relationship between alcohol consumption and renal cell cancer risk using data from the NIH-AARP Diet and Health Study, analyzing 1814 RCC cases.
Potential Biases
Potential misclassification of former heavy drinkers as non-drinkers.
Limitations
Alcohol consumption was assessed only at baseline, limiting the ability to examine lifetime consumption or changes in drinking patterns.
Participant Demographics
Participants were aged 50-71 years, with a mix of men and women, primarily white, non-Hispanic.
Statistical Information
P-Value
0.004
Confidence Interval
0.63–0.90
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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